Skypiea's existence gives a new vision of One Piece World geography. As explained by Gan Fall and Captain McKinley, there are more sky islands. Later, at the end of the Sabaody Archipelago Arc, Kuma sent Nami off to Weatheria. Robin discovers a Poneglyph with a mark from Gol D. Roger. In Sabaody Archipelago, she asks Rayleigh about it, and he declares that the Roger Pirates had discovered the true history. Also, the ancient weapon Poseidon would be mentioned. In the Fishman Island Arc, Robin would discover that Poseidon was actually the Mermaid Princess' name during the Void Century. This would foreshadow Shirahoshi's connection to the ancient weapon. The huge amount of gold the Straw Hats found in Skypiea was ultimately used to finance building of the Thousand Sunny. The Skypieans offered the Straw Hats the golden pillar from the Belfry, but after a misunderstanding they ended up turning it down. After the timeskip it somehow found its way into the hands of Bellamy after he discovered the legend of Sky Island to be true. He gave it to Doflamingo to gain his good graces, but it is unclear what transpired, whether he stole it or acted as an 'emissary' of the Straw Hats. This arc would be a turning point for Chopper, as he would learn to fight on his own and not rely on others and gain more bravery in his future fights. Usopp made use of the Dials by upgrading his and Nami's weapons with them making the Kabuto and the Perfect Clima-Tact. This is also the first appearance of Klabautermann. He would not be seen again until the Water 7 Arc. This arc also introduced the ability Mantra, which was finally revealed in the Post-War Arc to be a form of Haki known as Kenbunshoku Haki.
Skypeia was a very important ark in the introduction of Haki and the understanding of how powerful a well used devil fruit can be used. Enels use of "Mantra" (observation haki) was the first use of observation in the whole series which allowed understanding and recolection of observation haki when it was later properly introduced. Skypeia was also the first introduction of Doflamingo. Skypeia also furthered the idea that luffy was following the same path as Roger.